Mayor Tom Kane, despite being the most effective Chicago mayor in recent history, has a degenerative brain disorder ripping everything away from him. He can't trust his memory, his closest allies, or even himself. Kane's wife Meredith knows nothing. Kitty O'Neil, Kane's advisor, has her suspicions but stays silent. And Kane's political advisor Ezra Stone, a Yale graduate with a rough edge, remains questionless. Only Emma, Kane's estranged daughter, has a chance of learning his secret. This is going to be the toughest term yet for the Boss.